Cardiorespiratory and hemogasometric effects of epidural ketamine and its associations with morphine and xylazine in sheep

This study aimed to evaluate the cardiorespiratory and hemogasometric effects of epidural ketamine its associations with morphine xylazine in ewes submitted transcervical cervix transposition a hegar dilator. Ten Santa Inês breed were studied cross over model where three protocols (GK = 2.0 mg kg-1; GKM kg-1 + 0.1 GKX 0.05 kg-1) compared among each other control treatment (GS= saline 1 mL/7.5 kg). The assessed variables heart rate, respiratory frequency, ear temperature, non-invasive blood pressure analysis. All parameters at baseline then sedated an association acepromazine (0.1 kg -1) diazepam (0.2 -1). minutes after sedation all reassessed afterwards injections performed. Hemogasometry was repeated 15 30 05, 15, 30, 45 60 epidural. showed slight depression lower levels PO2 compensatory increase frequency. presented temperature mean. few when control. Epidural isolated considered best option for short procedures as obstetric manipulations sheep due stability using associations.